CHONDROITIN SULFATE PROTEOGLYCANS REGULATE THE GROWTH, DIFFERENTIATION AND MIGRATION OF MULTIPOTENT NEURAL PRECURSOR CELLS THROUGH THE INTEGRIN SIGNALING PATHWAY

Chondroitin sulfate proteoglycans regulate the growth, differentiation and migration of multipotent neural precursor cells through the integrin signaling pathway

Abstract Background Neural precursor cells (NPCs) are defined by their ability to proliferate, self-renew, and retain the potential to differentiate into neurons and glia.Deciphering the factors that regulate their behaviors will greatly aid in their use as potential therapeutic agents or targets.Chondroitin sulfate proteoglycans (CSPGs) are promin

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The Main Risk Factors in Type 2 Diabetes for Cognitive Dysfunction, Depression, and Psychosocial Problems: A Systematic Review

The aim of this study is to analyze the risk factors that lead to cognitive impairment, depression, and psychosocial problems in type 2 diabetes and discern what aspects they have in common.Type 2 diabetes is associated with a higher risk of cognitive impairment, including dementia, which in turn increases the risk of hospitalization, falls, and pr

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